Table 2 Bias of estimated gene expression levels (up:down = 9:1) for simulated cDNA microarray data with the R-I plots similar to Figure 2.
From: A robust two-way semi-linear model for normalization of cDNA microarray data
Percentage of DEG | Descriptive Statistics | ||||||
|---|---|---|---|---|---|---|---|
| Â | Method | Mean | Minimum | 25% Quantile | Median | 75% Quantile | Maximum |
1% | OLS | 0.0000 | -1.2716 | -0.0212 | -0.0033 | 0.0154 | 1.2441 |
| Â | Huber | 0.0000 | -1.0330 | -0.0161 | -0.0020 | 0.0115 | 0.9925 |
| Â | Tukey | 0.0001 | -0.8617 | -0.0153 | -0.0014 | 0.0112 | 0.8462 |
| Â | LOWESS | -0.0017 | -1.2685 | -0.0226 | -0.0047 | 0.0137 | 1.2367 |
5% | OLS | 0.0000 | -0.8941 | -0.0412 | -0.0209 | 0.0019 | 1.4051 |
| Â | Huber | 0.0000 | -0.7785 | -0.0326 | -0.0167 | 0.0007 | 1.1751 |
| Â | Tukey | 0.0000 | -0.7195 | -0.0299 | -0.0146 | 0.0017 | 1.0581 |
| Â | LOWESS | -0.0005 | -0.8995 | -0.0384 | -0.0182 | 0.0008 | 1.3993 |
10% | OLS | 0.0000 | -1.1402 | -0.0705 | -0.0441 | -0.0125 | 1.2574 |
| Â | Huber | 0.0000 | -0.9240 | -0.0578 | -0.0353 | -0.0096 | 1.0326 |
| Â | Tukey | 0.0000 | -0.8245 | -0.0521 | -0.0313 | -0.0064 | 0.9551 |
| Â | LOWESS | -0.0050 | -1.1332 | -0.0666 | -0.0429 | -0.0207 | 1.2736 |
20% | OLS | 0.0000 | -1.4381 | -0.1108 | -0.0742 | -0.0336 | 1.3336 |
| Â | Huber | 0.0000 | -1.1569 | -0.0927 | -0.0607 | -0.0247 | 1.1176 |
| Â | Tukey | 0.0000 | -1.0430 | -0.0841 | -0.0540 | -0.0175 | 0.9757 |
| Â | LOWESS | -0.0325 | -1.4180 | -0.1352 | -0.1009 | -0.0634 | 1.2991 |
40% | OLS | 0.0000 | -1.4475 | -0.1943 | -0.1348 | 0.1870 | 1.3258 |
| Â | Huber | 0.0000 | -1.2461 | -0.1620 | -0.1061 | 0.1474 | 1.1159 |
| Â | Tukey | 0.0000 | -1.1429 | -0.1460 | -0.0907 | 0.1294 | 0.9800 |
| Â | LOWESS | -0.1488 | -1.6159 | -0.3340 | -0.2603 | 0.0182 | 1.1444 |