Figure 1
From: transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Theoretical gain in speed from performing a translated alignment. The figure reveals there is always a performance advantage in aligning any given proportion of the protein-coding DNA sequences in a data set via their amino-acid translations with the remaining DNA sequences subsequently profile-aligned to them. The curve as shown is based on the assumption that the translated alignment is 9x faster, on average, than the respective DNA alignment; other values produce nearly identical curves of different scales.