Table 4 Comparison of sorted class list against GENERATOR clustering with itraconanzole dataset. The table shows the sorted list of over-represented functional classes for itraconanzole dataset. Only the 25 best scoring classes are shown to limit the size. Columns are same as in table 2. Notice that most of the functional classes are associated with amino acid biosynthesis. Detailed results are shown in table 8 [see Additional file 8].
From: Theme discovery from gene lists for identification and viewing of multiple functional groups
Rank | Class | O.log(p) | In cluster |
|---|---|---|---|
1 | amino acid biosynthesis | 19.07 | I |
2 | amine biosynthesis | 18.08 | I |
3 | carboxylic acid metabolism | 14.77 | I |
4 | organic acid metabolism | 14.77 | I |
5 | amino acid metabolism | 14.70 | I |
6 | amino acid and derivative metabolism | 13.75 | I |
7 | amine metabolism | 13.02 | I |
8 | arginine biosynthesis | 11.28 | I |
9 | steroid metabolism | 8.89 | II |
10 | nitrogen metabolism | 8.79 | not reported |
11 | urea cycle intermediate metabolism | 8.66 | not reported |
12 | arginine metabolism | 8.66 | not reported |
13 | Biosynthesis | 8.52 | I, II |
14 | transaminase activity | 8.32 | not reported |
15 | transferase activity, transferring nitrogenous groups | 8.32 | not reported |
16 | glutamine family amino acid biosynthesis | 8.16 | not reported |
17 | sterol metabolism | 8.02 | II |
18 | glutamine family amino acid metabolism | 7.99 | I |
19 | sterol biosynthesis | 7.77 | II |
20 | steroid biosynthesis | 7.69 | II |
21 | ergosterol biosynthesis | 6.22 | II |
22 | ergosterol metabolism | 6.22 | II |
23 | aromatic compound metabolism | 5.85 | not reported |
24 | branched chain family amino acid metabolism | 5.61 | not reported |
25 | cyclohydrolase activity | 5.50 | not reported |