Skip to main content

Table 4 Comparison of sorted class list against GENERATOR clustering with itraconanzole dataset. The table shows the sorted list of over-represented functional classes for itraconanzole dataset. Only the 25 best scoring classes are shown to limit the size. Columns are same as in table 2. Notice that most of the functional classes are associated with amino acid biosynthesis. Detailed results are shown in table 8 [see Additional file 8].

From: Theme discovery from gene lists for identification and viewing of multiple functional groups

Rank Class O.log(p) In cluster
1 amino acid biosynthesis 19.07 I
2 amine biosynthesis 18.08 I
3 carboxylic acid metabolism 14.77 I
4 organic acid metabolism 14.77 I
5 amino acid metabolism 14.70 I
6 amino acid and derivative metabolism 13.75 I
7 amine metabolism 13.02 I
8 arginine biosynthesis 11.28 I
9 steroid metabolism 8.89 II
10 nitrogen metabolism 8.79 not reported
11 urea cycle intermediate metabolism 8.66 not reported
12 arginine metabolism 8.66 not reported
13 Biosynthesis 8.52 I, II
14 transaminase activity 8.32 not reported
15 transferase activity, transferring nitrogenous groups 8.32 not reported
16 glutamine family amino acid biosynthesis 8.16 not reported
17 sterol metabolism 8.02 II
18 glutamine family amino acid metabolism 7.99 I
19 sterol biosynthesis 7.77 II
20 steroid biosynthesis 7.69 II
21 ergosterol biosynthesis 6.22 II
22 ergosterol metabolism 6.22 II
23 aromatic compound metabolism 5.85 not reported
24 branched chain family amino acid metabolism 5.61 not reported
25 cyclohydrolase activity 5.50 not reported
\