Table 1 Transcription factor significance. The 15 most significant transcription factors (TF) in the van 't Veer et al. [15] data set, and their number of downstream targets (DT). p-values are based on the Group Correlation Score. In all 54 TFs were studied for this data set. ER pathway notation as in Table 1.
From: Signal transduction pathway profiling of individual tumor samples
TF | # of DT | p-value |
|---|---|---|
NF-κ B | 19 | 4e-04 |
RelA | 11 | 8e-04 |
ER Complex(i) | 50 | 2e-03 |
NF-κ B1 | 10 | 2e-03 |
STAT1α | 2 | 6e-03 |
C/EBPα | 21 | 7e-03 |
ER-induced (v) | 5 | 7e-03 |
ER | 77 | 8e-03 |
STAT6 | 6 | 8e-03 |
ER(v) | 7 | 2e-02 |
GATA-1 | 7 | 2e-02 |
Elk-1 | 4 | 6e-02 |
c-Rel | 3 | 6e-02 |
STAT4 | 3 | 7e-02 |
SMAD-3 | 6 | 7e-02 |