Figure 1
Comparisons based on simulated data from the beta-binomial distribution. This figure shows the receiver operating characteristic curves (ROC) of the four tests applied to datasets generated from the beta-binomial distribution with various magnitudes of overdispersion (φ) (shown on the top of each graph). For a specific φ, 10,000 observations (tags) are simulated; 5,000 are generated under the assumption that p A = p B and the remaining from p B = 2 p A , where p A and p B are the mean proportions of the two groups and p A = 0.0002 (i.e. 10 out of 50,000). For figures generated under other conditions, see Additional file 1.