Figure 4

Effect of codon bias discrepancy on behaviour of codon usage measures. The figure shows how the measures react to codon discrepancy, i.e. when the amino acids within a sequence differ in amounts of bias. The value on the y axis is the amount of overestimation (in % of the methods' dynamic ranges) that occurs as discrepancy is introduced; this was determined by examining 10000 generated sequences for each length (x axis) and method. Figure 4a uses frequency tables adopted from Fuglsang [35], and 4b uses the authors' own frequency tables.