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Figure 1 | BMC Bioinformatics

Figure 1

From: PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability

Figure 1

Main steps in the PSI-BLAST-ISS execution. PSI-BLAST-ISS comprises seven main steps to produce consensus sequence alignment starting with the target sequence. The position-specific alignment reliability can be estimated either from individual target-template multiple alignments obtained in step 6 or from the combined alignment of consensus template sequences (step 7). For example, in this figure (step 7) only two template sequences are estimated to be reliably aligned with the last helix of the target, other templates lack consensus in this region.

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