Figure 4

GO tree depth calculation. A section of the GO tree is depicted here. The directed acyclic nature of GO is shown by the red and black trails leading to the same node. The depth of a node is its distance from the root. Thus the node for GO:0003700 at the bottom has different depths on the tree, depending on the path traversed to get to it from the root. We use the higher number (6, the greater depth) as its depth for our calculations, which are described in the text.