Skip to main content
Figure 4 | BMC Bioinformatics

Figure 4

From: Graph-representation of oxidative folding pathways

Figure 4

Three dimensional representation of the oxidative folding space of polypeptides with 4, 5 and 6 cysteine residues (A, B and C, respectively). The nodes represent intermediates, the number of disulfide bridges is indicated with numbers on the left of each panel. The edges indicate disulfide exchange transitions. Zero indicates the fully reduced state, nodes in the lowest plane are the fully oxidized intermediates, one of which is usually the native state. Edges within the same plane indicate shuffling reactions (interchange between two protein-bound disulfides), edges between planes are redox transitions in which a disulfide bridge is created or abolished. A simple visualization tool written for the Tulip package http://www.tulip-software.org/ can be obtained from V.A. vilagos@brc.hu

Back to article page