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Table 2 Disulfied intermediates experimentally observed in the oxidative folding of various proteins

From: Graph-representation of oxidative folding pathways

Protein Disulfide intermediates1 Ref.
Bovine pancreatic trypsin inhibitor (BPTI) 3–5; 1–6; 3–5, 1–2;
3–5, 1–4; 3–5, 2–4;
1–6, 2–4; 3–5, 1–6;
1–6, 3–5, 2–4;
[26, 27]
Insulin-like growth factor (IGF) 2–6; 2–6, 3–5; 2–6, 1–4;
2–6, 4–5; 2–6, 1–3;
2–6, 1–3, 4–5; 1–4, 2–6, 3–5;
[28-30]
Epidermal growth factor (EGF) 2–3; 1–2; 4–6; 5–6;
3–4; 2–4, 5–6; 2–5, 3–4;
1–6, 2–5, 3–4; 1–2, 3–4, 5–6;
1–3, 2–4, 5–6;
[31]
  1. 1The intermediates are described with the notation given in Figure 2. The native disulfide connectivity is in bold, the fully reduced species is not included.