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Figure 2 | BMC Bioinformatics

Figure 2

From: Sample phenotype clusters in high-density oligonucleotide microarray data sets are revealed using Isomap, a nonlinear algorithm

Figure 2

Isomap analysis of the spinal cord injury data set. Three-dimensional Isomap models were generated from 170 rat high density oligonucleotide arrays with 8,799 genes on each array as described in Systems and Methods. Samples were classified based on the A: time, B:location, and C:severity of the spinal cord injury. Sphere diameters express the 95 percentile distance from the nearest neighbor within the group. Neighborhood size: k = 3. D: Residual variance after the application of Isomap, MDS, and PCA models. See text for more detail. Animated images are presented in Additional Files 1, 2, 3.

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