Figure 6

Human Notch1 functional report. The browser window shows a Web page with part of an automatically generated functional report. One of the orthologs (NTC1_MOUSE) to the query sequence (NOTCH_HSA) is shown, including some associated functional terms. At the end of each phylogenomic pipeline (Figure 5), after orthologs detection was produced on the consensus tree, an additional process is run. The goal of this process is to search on the Web experimentally verified functional data on proteins orthologous to the studied sequence. A HTML report synthesizing functional retrieved data is then built. It includes links to Web database and publication associated to retrieved functional terms. Current implementation of this system manages data coming from: GENE ONTOLOGY [51], MGD [52], and EST expression data available on NCBI Web site. This system is open for integration of other data sources.