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Table 5 Detailed statistics on the estimates of p0based on simulations of dependent data. The table displays the mean bias (true – estimated) and standard deviation of estimates for each level of true p0.

From: A comparative review of estimates of the proportion unchanged genes and the false discovery rate

True p 0   0.5 0.6 0.7 0.8 0.9 0.95 0.99
BUM mean bias -0.09885 -0.0744 -0.0524 -0.0308 -0.0525 -0.0493 -0.0100
  Sd 0.01555 0.0167 0.0169 0.0194 0.0520 0.0088 0.0010
SPLOSH mean bias -0.15811 -0.1179 -0.0710 -0.02570 0.0180 0.0318 0.06761
  Sd 0.02702 0.0309 0.0338 0.0398 0.0423 0.0379 0.0560
QVALUE mean bias -0.15089 -0.1217 -0.0895 -0.0593 -0.0307 -0.0142 0.0093
  Sd 0.02661 0.0306 0.0302 0.0345 0.0368 0.0309 0.0255
Bootstrap LSE mean bias -0.18009 -0.1499 -0.1080 -0.0691 -0.0313 -0.0126 0.0084
  Sd 0.04242 0.0382 0.0351 0.0326 0.0299 0.0269 0.0232
SEP mean bias -0.15525 -0.1238 -0.0915 -0.0584 -0.0277 -0.0134 0.0138
  Sd 0.02419 0.0239 0.0241 0.0265 0.0269 0.0203 0.0201
LSL Mean Bias -0.2710 -0.2203 -0.1667 -0.1110 -0.0554 -0.0292 0.0017
  Sd 0.13333 0.1119 0.0902 0.0671 0.0410 0.0221 0.0165
Mgf mean bias -0.18322 -0.1468 -0.1349 -0.0898 -0.0460 -0.0235 0.0007
  Sd 0.04633 0.0401 0.0140 0.0153 0.0160 0.0153 0.0128
PRE mean bias 0.14088 -0.1091 -0.0770 -0.0442 -0.0152 -0.0021 0.0194
  Sd 0.02300 0.0239 0.0239 0.0291 0.0310 0.0269 0.0248