Figure 3

Variable location of interacting amino acid residues in the HMG domain. Sequence specific interaction by the high mobility group (SMART: HMG) domain (green) is achieved by an amino acid side chain (pink) pointing into the DNA double helix (blue). The interaction is achieved by a phenylalanine in figure 3a [28] or by a serine residue in 3b [27]. The sequence alignment (figure 3c) reveals that these two interacting residues are not located at corresponding position.