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Table 5 Specificity value for each method at the sensitivity = 50% level (5 proteins set)

From: Improved prediction of critical residues for protein function based on network and phylogenetic analyses

Method

Specificity

Proportion of predicted residues

Union set (10)

89%

18%

Conseq

85%

22%

Intersection set (9)

85%

23%

Closeness

85%

22%

Connectivity (4)

85%

22%

2-connectivity (3)

83%

28%

Betweenness

80%

27%

1/cluster (5)

80%

27%

Hssp

80%

24%

1/eccentricity

76%

30%

  1. For every method, results are obtained in average over the set of five proteins. Numbers are obtained by calculating the average as in Table 1. For each method, we indicate the value of the specificity and the proportion of residues that are predicted when the sensitivity is equal to 50%.