Figure 4

Examples of correlations between gene expression and proteome parameters. Comparison of the medians of gene expression (●) and medians of the observed/expected ratio of proteins associated with functional and structural variables (□). a, Protein amino acid phosphorylation, time point 3 in the CD3 dataset; b, SCOP classification of α/β proteins, time point 6 in the CD3 dataset; c, Gene ontology for receptor activity, time point 5 in the CD3/CD28-costimulated dataset; and d, Gene ontology for protein biosynthesis, time point 3 in the CD3/CD28-costimulated dataset. The graphs indicate both positive and negative correlations. The clusters are arranged so that the medians of gene expression along the time points are in descending order.