Skip to main content

Table 2 Assignments for the pathway isoleucine biosynthesis I. Only reactions with alternative assignments are listed (last column), and the selection number refers to Figure 2. For example, the top assignment selects the second gene (ILV1) to catalyze reaction 4.3.1.19. Assignments are sorted based on the normalized score. Second column marks which assignments are true assignments, and which are considered false assignments. For each assignment we list the total number of pairwise similarities, the number of positive and negative scoring pairs and the number of zero scoring pairs (when no expression data is available).

From: Automation of gene assignments to metabolic pathways using high-throughput expression data

Number

Match

Normalized Score

Number of Pairs

Positive Pairs

Negative Pairs

Zero Pairs

Assignments

1

+

10.32

10

10

0

0

4.3.1.19 : 2

4.1.3.18 : 2

2.6.1.42 : 1

2

+

9.54

10

10

0

0

4.3.1.19 : 2

4.1.3.18 : 1

2.6.1.42 : 1

3

+

7.37

10

10

0

0

4.3.1.19 : 2

4.1.3.18 : 2

2.6.1.42 : 2

4

-

6.49

10

8

2

0

4.3.1.19 : 3

4.1.3.18 : 2

2.6.1.42 : 1

5

+

6.30

10

9

1

0

4.3.1.19 : 2

4.1.3.18 : 1

2.6.1.42 : 2

6

-

6.08

10

6

0

4

4.3.1.19 : 1

4.1.3.18 : 2

2.6.1.42 : 1

7

-

5.52

10

6

0

4

4.3.1.19 : 1

4.1.3.18 : 1

2.6.1.42 : 1

8

-

5.00

10

7

3

0

4.3.1.19 : 3

4.1.3.18 : 1

2.6.1.42 : 1

9

-

4.78

10

8

2

0

4.3.1.19 : 3

4.1.3.18 : 2

2.6.1.42 : 2

10

-

3.84

10

6

0

4

4.3.1.19 : 1

4.1.3.18 : 2

2.6.1.42 : 2

11

-

3.00

10

6

4

0

4.3.1.19 : 3

4.1.3.18 : 1

2.6.1.42 : 2

12

-

3.00

10

5

1

4

4.3.1.19 : 1

4.1.3.18 : 1

2.6.1.42 : 2