Figure 4

Histograms of cross-diagnostic ROC areas for the multi-species network. (a) Histogram of ROC areas for whether descendent P _e -values are diagnostic of parent sets. (b) Histogram of ROC areas for cross pairing of sibling categories. (c) Histogram of ROC areas for all cross pairings of categories (excluding parent-descendent pairs) with distances of 3–16 in a GO graph. GO organizes categories as nodes on a graph and calculates the distance between category pairs on the same graph as the minimum number of arcs needed to traverse from one category node to another on the graph. For example, a parent and its child are separated by a distance of one and siblings are separated by distances of two. (d) Histogram of ROC areas for all cross pairings of categories (excluding parent-descendent pairs) with distances of 3–16 in a GO graph, created using randomized GO sets. (e) Histogram of cross-diagnostic ROC areas between GO category pairs (excluding parent-descendent pairs) in the subgraph below immune response. (f) Histogram of cross-diagnostic ROC areas between GO category pairs (excluding parent-descendent pairs) in the subgraph below cell cycle.