From: EXPANDER – an integrative program suite for microarray data analysis
Bicluster number | Num of Conditions | Num of Genes | Enriched GO (GOid, p-val) | Enriched TF binding site signatures (TRANSFAC id, p-val) | Comments |
---|---|---|---|---|---|
106 | 9 | 79 | DNA Replication (GO:0006260, 5.3 × 10-9) | E2F (M00918, 1.3 × 10-7) | Down-regulation of DNA replication genes in fibroblasts exposed to DDT or Menadione. |
40 | 33 | 74 | Mitosis (GO:0007067, 9.3 × 10-19) | NF-Y (M00287, 6.7 × 10-22) IRF-7 (M00453, 9.5 × 10-5) | Down-regulation of mitotic genes in response to various stresses. |
104 | 41 | 13 | Mitosis (GO:0007067, 3.3 × 10-10) | NF-Y (M00287, 3.4 × 10-9) | Down-regulation of mitotic genes in response to various stresses. |
16 | 5 | 89 | Carboxylic acid metabolism (GO:0019752, 3.4 × 10-8) | --- | Genes activated in Hela cells in response to Tunicamycin and Menadione |
1 | 6 | 145 | Response to unfolded protein (GO:0006986, 1.2 × 10-7) | --- | Genes activated in Hela cells in response to heat shock |
9 | 7 | 142 | Response to unfolded protein (GO:0006986, 7.3 × 10-9) | AP-2alpha (M00469, 5.6 × 10-4) | Genes activated in K562 cells in response to heat shock |
111 | 10 | 24 | Response to unfolded protein (GO:0006986, 1.5 × 10-7) | --- | Genes that are activated by heat shock but repressed by crowding in Hela cells |
24 | 6 | 105 | Transcription corepressor (GO:0003714, 1.5 × 10-6) | HIF-1 (M00797, 6.9 × 10-4) | Genes activated in fibroblasts in response to DDT |
27 | 8 | 200 | --- | ---- | Genes activated in fibroblasts in response to oxidative stress (H2O2) |
61 | 9 | 134 | --- | ---- | Genes that are repressed by crowding in fibroblasts. |
53 | 22 | 51 | ---- | N-Myc(M00055, 2.7 × 10-6) | Genes that are repressed in both Hela cells and fibroblasts. |
89 | 9 | 115 | --- | AP-4 (M00005, 2.1 × 10-4) | Genes repressed in Hela cells in response to various stresses. |
123 | 10 | 31 | --- | NFkB (M00051, 7.1 × 10-4) | Genes activated in Hela cells in response to DDT. |