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Table 1 System performance measures. Performance was measured based on the program's ability to correctly discriminate CTT proteins from non-CTT proteins. MCC = Mathews' Correlation Coefficient [1].

From: Evaluating eukaryotic secreted protein prediction

Program TP FP TN FN Sensitivity Specificity MCC
TargetP 55 8 307 2 96% 87% 90%
SignalP3 NN – Cmax 52 48 267 5 91% 52% 62%
SignalP3 NN – Ymax 55 9 306 2 96% 86% 89%
SignalP3 NN – Smax 56 9 306 1 98% 86% 90%
SignalP3 NN – Smean 55 17 298 2 96% 76% 83%
SignalP3 NN – D 55 7 308 2 96% 89% 91%
SignalP3 HMM Cmax 46 9 306 11 81% 84% 79%
SignalP3 HMM Sprob 56 17 298 1 98% 77% 84%
SignalP2 NN – Ymax 56 14 301 1 98% 80% 86%
SignalP2 NN – Cmax 54 28 287 3 95% 66% 75%
SignalP2 NN – Smean 57 13 302 0 100% 81% 88%
SignalP2 NN – Smax 56 21 294 1 98% 73% 81%
SignalP2 HMM Sprob 57 21 294 0 100% 73% 83%
SignalP2 HMM Cmax 36 3 312 21 63% 92% 73%
Phobius 55 13 302 2 96% 81% 86%
PrediSi 52 12 303 5 91% 81% 83%
ProtComp NN 46 32 283 11 81% 59% 62%