Table 1 System performance measures. Performance was measured based on the program's ability to correctly discriminate CTT proteins from non-CTT proteins. MCC = Mathews' Correlation Coefficient [1].
Program | TP | FP | TN | FN | Sensitivity | Specificity | MCC |
|---|---|---|---|---|---|---|---|
TargetP | 55 | 8 | 307 | 2 | 96% | 87% | 90% |
SignalP3 NN – Cmax | 52 | 48 | 267 | 5 | 91% | 52% | 62% |
SignalP3 NN – Ymax | 55 | 9 | 306 | 2 | 96% | 86% | 89% |
SignalP3 NN – Smax | 56 | 9 | 306 | 1 | 98% | 86% | 90% |
SignalP3 NN – Smean | 55 | 17 | 298 | 2 | 96% | 76% | 83% |
SignalP3 NN – D | 55 | 7 | 308 | 2 | 96% | 89% | 91% |
SignalP3 HMM Cmax | 46 | 9 | 306 | 11 | 81% | 84% | 79% |
SignalP3 HMM Sprob | 56 | 17 | 298 | 1 | 98% | 77% | 84% |
SignalP2 NN – Ymax | 56 | 14 | 301 | 1 | 98% | 80% | 86% |
SignalP2 NN – Cmax | 54 | 28 | 287 | 3 | 95% | 66% | 75% |
SignalP2 NN – Smean | 57 | 13 | 302 | 0 | 100% | 81% | 88% |
SignalP2 NN – Smax | 56 | 21 | 294 | 1 | 98% | 73% | 81% |
SignalP2 HMM Sprob | 57 | 21 | 294 | 0 | 100% | 73% | 83% |
SignalP2 HMM Cmax | 36 | 3 | 312 | 21 | 63% | 92% | 73% |
Phobius | 55 | 13 | 302 | 2 | 96% | 81% | 86% |
PrediSi | 52 | 12 | 303 | 5 | 91% | 81% | 83% |
ProtComp NN | 46 | 32 | 283 | 11 | 81% | 59% | 62% |