Table 1 Key characteristics of used microarray data. The figures in curly brackets denote the number of samples belonging to each category. The number of probes comprises all probes for which data were available and which have not been filtered out in the preprocessing of the data (see methods for details). Abbreviations: ER, estrogen receptor status; AML, acute myeloid leukemia; t(A;B), balanced translocation of genetic material between chromosomes A and B; inv(16), inversion of a segment of chromosome 16; NN, normal karyotype.
Study | Cancer | Platform | Samples | Probes | Target Variable of Classification Analysis |
|---|---|---|---|---|---|
Dhanasekaran et al[22] | Prostate cancer | cDNA | 53 | 7769 | Tissue: tumor{34}, normal{19} |
Welsh et al[23] | Prostate cancer | oligo | 33 | 9023 | Tissue: tumor{24}, normal{9} |
Gruvberger et al[24] | Breast cancer | cDNA | 58 | 3300 | ER-status: positive{28}, negative{30} |
West et al[25] | Breast cancer | oligo | 49 | 5435 | ER-status: positive{25}, negative{24} |
Bullinger et al[26] | AML | cDNA | 52 | 14776 | Karyotype: t(8;21){11},t(15;17){12},inv(16){15}, NN{14} |
Valk et al[27] | AML | oligo | 97 | 13250 | Karyotype: t(8;21){22}, t(15;17){19},inv(16){23}, NN{33} |