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Table 1 Sensitivity and specificity. This table shows a comparison of the performances of various methods when applied to the genomic loci considered in this work. The sensitivity was calculated by taking the union of the miRNAs predicted by any method but confirmed experimentally. This set contains 38 elements.

From: Identification of clustered microRNAs using an ab initio prediction method

 

Altuvia et al. [23]

Berezikov et al. [10]

Xie et al. [21]

Our method

Conserved predictions in analyzed loci

87

179

29

36

Predictions not in Rfam 6.0

78

27

23

36

Predictions in Rfam 7.0 or in cloning set [19]

18

21

20

23

Sensitivity

47%

55%

53%

64%

Specificity

23%

77%

87%

64%

Uniquely predicted pre-miRNAs

4

4

1

4

Overlap of our predictions with others

10

14

14

-