Figure 4
From: The yeast kinome displays scale free topology with functional hub clusters
Cascade crawler output of Hubview. Gray spheres represent non-kinases while all other colored spheres represent kinases of varying degree. a) Depiction of closed loop TOR signaling: neither TOR protein is directly connected to another kinase indicating highly specified reaction. b) Depiction of open loop MAPK signaling: white spheres denote non-MAPK kinases that interact within and outside of the MAPK clusters representing possible regulatory and cross-talk channels associated with more complicated cellular behaviour.