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Figure 8 | BMC Bioinformatics

Figure 8

From: An ant colony optimisation algorithm for the 2D and 3D hydrophobic polar protein folding problem

Figure 8

Performance of ACO-HPPFP-3 and PERM on designed sequences in 2D HP. Left side: Unique minimal energy conformation of a designed sequence, D-1 (length 50, energy -19); ACO-HPPFP-3 reaches this conformation much faster than PERM when folding from the left end (mean run-time over 100 successful runs for ACO-HPPFP-3: 236 CPU seconds, compared to t1 = 3 795, t2 = 1, t exp = 2 CPU seconds for PERM). Right side: Unique native conformation of another designed sequence, D-2 (length 60, energy -17); ACO-HPPFP-3 finds this conformation much faster than PERM folding from either end (mean run-time over 100 successful runs for ACO-HPPFP-3: 951 CPU seconds, compared to t1 = 9 257, t2 = 19 356, t exp = 12 524 CPU seconds for PERM).

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