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Table 3 Differences between the p-values of the original two-part test and the two-part permutation test for genes with at least one truncation and small p-values (i.e. the p-value of the original test must be as small as mentioned under condition), a positive difference means that the two-part permutation test has a smaller p-value than the original test; data from the microarray experiment of Tschentscher et al. [11]

From: Two-part permutation tests for DNA methylation and microarray data

Condition

Number of remaining genes

Mean difference (± SD)

Median difference

Quartiles of the difference

p ≤ 0.1

514

0.0065 (± 0.0126)

0.0047

0.0012, 0.0124

p ≤ 0.05

336

0.0057 (± 0.0064)

0.0040

0.0018, 0.0095

p ≤ 0.01

114

0.0025 (± 0.0018)

0.0019

0.0010, 0.0035

p ≤ 0.001

19

0.0006 (± 0.0003)

0.0006

0.0003, 0.0009