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Table 5 Results of the simulation study: Powers of the original two-part test and the two-part permutation test; 5,000 data sets with n1 = n2 = 10 were generated for each configuration (notation as in Table 4, significance level α = 0.05)

From: Two-part permutation tests for DNA methylation and microarray data

Configuration

Original two-part test

Two-part permutation test

p1 = p2 = 0, μ = 2.5

0.82

0.93

p1 = p2 = 0.3, μ = 2.5

0.67

0.67

p1 = 0.4, p2 = 0.2, μ = 2.5

0.76

0.75

p1 = 0.2, p2 = 0.4, μ = 2.5

0.74

0.74

p1 = 0, p2 = 0.3, μ = 2.5

0.93

0.96

p1 = 0.3, p2 = 0, μ = 2.5

0.95

0.97

p1 = 0, p2 = 0.4, μ = 0

0.45

0.47

cutoff value = 0.5, μ = 2.5

0.85

0.90

cutoff value = 1, μ = 2.5

0.92

0.92