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Table 10 cluster size distribution with and without false positives

From: The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks

Dataset

Number Edges Removed

Edges Removed %

Nodes per Cluster

   

1

2–5

6–20

21–50

51–200

201+

   

Number of Clusters in Size Range

Lehner

57

14%

1

6

10

4

1

0

Lehner plus False Positive Edges(FPE)

57

12.3%

1

6

11

2

2

0

Lehner minus 68 FPE

57+68*

26.9%

32

6

9

5

1

0

Lehner random edges removed**

57+68*

26.9%

39.7 ± 3.2

6.5 ± 1.0

13.4 ± 2.1

4.1 ± 1.1

0.05 ± 0.2

0 ± 0

Ito minus 26 FPE

57+26*

1.9%

25

183

4

0

0

1

Ito minus 26 random edges

57+26*

1.9%

11

189

5

0

0

1

  1. * edges removed for clustering + false positive or random edges removed
  2. **Lehner plus FPE with 68 edges removed at random (for 100 replicates mean ± standard deviation)
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BMC Bioinformatics

ISSN: 1471-2105

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