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Table 1 S. cerevisiae and orthologous co-expression of known Protein interactions

From: Computational verification of protein-protein interactions by orthologous co-expression

GENE 1

GENE 2

S. cerevisiae Co-expression

Orthologous Co-expression

  

correlation

p-value

D. melanogaster

C. elegans

H. sapiens

p-value

CDC28

CLB2

-0.07

0.74

*

0.77

0.59

3.7e-04

 

CLB4

-0.06

0.71

0.85

0.77

0.59

1.0e-05

 

CDC6

-0.03

0.60

0.77

0.32

0.37

2.6e-04

 

CLB3

-0.01

0.52

0.85

0.77

0.59

1.0e-05

 

CLB1

0.05

0.30

*

0.65

0.59

7.3e-04

 

CLB5

0.06

0.27

0.87

0.65

0.45

3. 0e-05

DMC1

PDC5

-0.09

0.80

0.59

*

0.17

6.8e-03

 

PDC1

-0.05

0.67

0.59

*

0.17

6.8e-03

 

RIS1

-0.02

0.56

*

0.34

0.52

4.3e-03

PRP9

RIS1

0.02

0.41

*

0.28

0.62

3.7e-03

 

PRP11

0.05

0.30

0.88

0.35

0.33

1.6e-04

 

NOG2

0.07

0.24

0.41

0.33

0.66

3.5e-04

SSN6

CUS1

-0.06

0.71

0.76

0.32

*

5.4e-04

 

SNP1

0.08

0.21

0.79

0.21

*

2.1e-03

PAB1

SGN1

-0.17

0.93

0.56

0.19

0.26

2.4e-03

 

RNA14

-0.06

0.71

0.42

0.17

0.24

5.8e-03

PFS2

RNA14

-0.03

0.60

0.44

0.31

-

8.5e-03

HAT1

HAT2

-0.04

0.33

0.86

0.19

0.22

7.3e-04

SIT4

TAP42

-0.16

0.92

0.54

-

0.36

4.3e-03

TRS23

BET3

-0.10

0.82

*

0.20

0.52

8.1e-03

DNA2

RAD27

-0.01

0.52

*

0.41

0.47

3.9e-03

PRP8

SNU114

0.05

0.30

*

0.60

0.57

8.7e-04

HRB1

MTR10

-0.07

0.74

0.56

0.27

0.27

1.5e-03

BTT1

EGD2

-0.08

0.77

0.42

0.52

0.59

2.0e-04

GPA1

STE11

0.07

0.24

0.55

0.25

0.37

1.1e-03

UBA2

AOS1

0.08

0.21

0.74

0.17

0.41

5.4e-04

SPT15

BRF1

0.09

0.19

0.72

0.21

0.23

1.1e-03

TAF5

TAF9

0.05

0.30

0.86

-

0.18

2.1e-03

LSM5

KEM1

0.04

0.33

-

0.37

0.65

2.3e-03

RPB3

MED7

0.01

0.45

*

0.49

0.32

5.3e-3

  1. * denotes that at least one of the corresponding orthologs did not have expression data.
  2. - denotes that there is no pair of corresponding orthologs.