Figure 7From: In silico microdissection of microarray data from heterogeneous cell populationsDetecting differentially expressed genes. A set of genes which are not found to be significantly differentially expressed based on the heterogeneous measurements (samples #2 and #4, blue circles). After the inversion of the mixing effect, however, the expression difference between the estimated pure colon cancer cells and lymphocytes (red stars) meet even a more stringent criterion of differential expression. The horizontal and vertical axes correspond to the fraction of lymph node cells and the normalized expression value, respectively. Symbols: the heterogeneous samples (blue circles), the estimated expression values (red stars), and the measured expression values of the pure colon cancer cells (blue squares). See text for more details.Back to article page