Table 1 Performance of seven protein multi-alignment programs on the IRMBASE 1.0 database of benchmark alignments. Percentage values are sum-of-pairs scores, i.e. the percentage of correctly aligned residue pairs of ROSE motifs contained in the IRMBASE sequence families.
From: DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Method | ref1 | ref2 | ref3 | Total |
|---|---|---|---|---|
DIALIGN-T | 94.07% | 92.69% | 92.68% | 93.14% |
DIALIGN 2.2 | 92.26% | 92.72% | 91.87% | 92.28% |
T-COFFEE 1.37 | 91.18% | 85.61% | 87.81% | 88.20% |
PROBCONS 1.09 | 66.74% | 68.30% | 77.92% | 70.98% |
POA V2 | 90.26% | 43.61% | 36.85% | 56.91% |
MUSCLE 3.5 | 36.16% | 37.84% | 52.30% | 42.10% |
CLUSTAL W 1.83 | 8.02% | 12.69% | 20.16% | 13.62% |