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Table 5 Percentage of sequence families where DIALIGN-T is outperformed on IRMBASE 1.0 by alternative methods according to the sum-of-pairs score. The symbol + denotes statistically significant superiority, - statistically significant inferiority and 0 non-significant superiority or inferiority of DIALIGN-T, respectively. Significance has been calculated according to the Wilcoxon Matched Pairs Signed Rank Test with p ≤ 0.05).

From: DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment

Method ref1 ref2 ref3 Total
DIALIGN 2.2 20.00%+ 23.33%0 23.33%+ 22.22%+
T-COFFEE 1.37 40.00%0 31.67%+ 41.67%+ 37.78%+
PROBCONS 1.09 20.00%+ 15.00%+ 21.67%+ 18.89%+
POA V2 16.67%+ 0.00%+ 0.00%+ 5.55%+
MUSCLE 3.5 5.00%+ 5.00%+ 0.00%+ 3.33%+
CLUSTAL W 1.83 0.00%+ 0.00%0 0.00%0 0.0%+