Evaluation of methods for predicting the topology of β-barrel outer membrane proteins and a consensus prediction method

Table 2 Multivariate Analysis of Variance (MANOVA) using as dependent variables the vector of the 5 measures of accuracy.

A.	Wilk's Λ	df1	df2	F	p-value
overall	0.1981	105	2029	7.59	<10^-4
type	0.8455	5	414	15.13	<10^-4
method	0.2582	50	1891	13.08	<10^-4
*typemethod**	0.8541	50	1891	1.33	0.0619
B.
overall	0.4511	15	1193	26.58	<10^-4
type	0.8609	5	432	13.96	<10^-4
hmm	0.5441	5	432	72.40	<10^-4
*typehmm**	0.9585	5	432	3.74	0.0025

A. Model that includes as independent variables the individual methods (11 factors), the type of the sequence (barrel/precursor) and their interaction term. B. Model that includes as independent variables the type of the method (HMM/not-HMM), the type of the sequence (barrel/precursor) and their interaction term. We report the Wilk's lambda statistic (Wilk's Λ), the degrees of freedom of the numerator (df1), the degrees of freedom of the denominator (df2), the F statistic (F) and the corresponding p-value (p-value).

ISSN: 1471-2105