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Figure 10 | BMC Bioinformatics

Figure 10

From: Comparative mapping of sequence-based and structure-based protein domains

Figure 10

A Pfam family corresponds to two different sets of SCOP domains, each consisting of a series of three domains. The PDB proteins 1a6d and 1iokG are used for the illustration. The SCOP domains a.129.1.1 and a.129.1.2 are marked in purple. The SCOP domains d.56.1.1 and d.56.1.2 are marked in red. The SCOP domains c.8.5.1 and c.8.5.2 are marked in blue. The Pfam domain Cpn60_TCP 1 is marked in green. (A)The Pfam family Cpn60_TCP1 is mapped to the set of SCOP domain families: {a.129.1.2 + d.56.1.2 + c.8.5.2}. (B)The Pfam family Cpn60_TCP1 is mapped to the set of SCOP domain families: {a.129.1.1 + d.56.1.1 + c.8.5.1} (C)Illustration of the insertion process which supports the SCOP domain definitions for this particular case. The SCOP domain families a.129.1.1 and a.129.1.2 are the parent domains. Later the SCOP domain families d.56.1.1 and d.56.1.2 are inserted into a.129.1.1 and a.129.1.2, respectively. Finally the SCOP domain c.8.5.1 is inserted into d.56.1.1, and the SCOP domain c.8.5.2 is inserted into d.56.1.2.

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