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Table 3 The number of enzymes for selected metabolic pathways from KEGG.

From: Columba: an integrated database of proteins, structures, and annotations

Metabolic pathway

Enzyme total

CATH class

 

Total

with str.

coverage

a / b

a

b

Few

all pathways

1 952

508

26,0

443

114

107

15

Fatty acid biosynthesis (path 1)

14

7

50,0

6

0

2

0

Oxidative phosphorylation

10

5

50,0

3

3

3

1

Streptomycin biosynthesis

14

7

50,0

6

0

1

0

Pyrimidine metabolism

59

30

50,8

29

6

5

0

Selenoamino acid metabolism

21

11

52,3

11

2

2

1

Pentose phosphate pathway

33

18

54,5

17

2

2

2

Methionine metabolism

23

13

56,5

13

3

1

1

One carbon pool by folate

23

13

56,5

13

2

1

0

Phe, Tyr and Trp biosynthesis

31

19

61,2

18

6

2

0

Glycolysis / Gluconeogenesis

38

24

63,1

24

2

5

2

Reductive carboxylate cycle (CO2 fixation)

13

9

69,2

8

3

1

1

Aminoacyl-tRNA biosynthesis

21

16

76,1

16

8

6

0

Carbon fixation

23

18

78,2

18

2

3

0

  1. The sum of observations in CATH classes can be higher than the number of enzymes with structures from the pathway, because in one chain, several domains with distinct folds can occur.