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Table 1 PREP-Mt performance results subdivided by gene

From: PREP-Mt: predictive RNA editor for plant mitochondrial genes

Gene

No. of Species

TP

TN

FP

FN

Specificity

Sensitivity

Accuracy

Balanced Accuracy

Complex I

   nad1

10

135

1632

14

33 (2)

99.1

80.4 (98.5)

97.4 (99.1)

89.8 (98.8)

   nad2

9

140

2337

22

42 (9)

99.1

76.9 (94.0)

97.5 (98.8)

88.0 (96.5)

   nad3

22

274

1217

8

47 (4)

99.3

85.4 (98.6)

96.4 (99.2)

92.4 (99.0)

   nad4

9

133

2358

19

12 (1)

99.2

91.7 (99.3)

98.8 (99.2)

95.5 (99.2)

   nad4L

8

49

303

5

0 (0)

98.4

100.0 (100.0)

98.6 (98.6)

99.2 (99.2)

   nad5

10

122

3647

29

10 (4)

99.2

92.4 (96.8)

99.0 (99.1)

95.8 (98.0)

   nad6

10

70

995

16

15 (3)

98.4

82.4 (95.9)

97.2 (98.2)

90.4 (97.2)

   nad7

8

117

1655

5

22 (1)

99.7

84.2 (99.2)

98.5 (99.7)

91.9 (99.4)

   nad9

12

75

1236

7

5 (3)

99.4

93.8 (96.2)

99.1 (99.2)

96.6 (97.8)

Complex II

   sdh3

7

6

391

12

11 (2)

97.0

35.3 (75.0)

94.5 (96.6)

66.2 (86.0)

   sdh4

8

10

361

14

16 (3)

96.3

38.5 (76.9)

92.5 (95.6)

67.4 (86.6)

Complex III

   cob

13

117

2834

19

25 (8)

99.3

82.4 (93.6)

98.5 (99.1)

90.9 (96.5)

Complex IV

   cox1

9

38

2936

7

7 (5)

99.8

84.4 (88.4)

99.5 (99.6)

92.1 (94.1)

   cox2

19

193

2644

22

33 (11)

99.2

85.4 (94.6)

98.1 (98.9)

92.3 (96.9)

   cox3

12

80

1793

21

11 (2)

98.8

87.9 (97.6)

98.3 (98.8)

93.4 (98.2)

Complex V

   atp1

10

21

2926

10

8 (1)

99.7

72.4 (95.5)

99.4 (99.6)

86.0 (97.6)

   atp4

7

51

730

21

18 (8)

97.2

73.9 (86.4)

95.2 (96.4)

85.6 (91.8)

   atp6

12

88

1893

11

10 (2)

99.4

89.8 (97.8)

99.0 (99.3)

94.6 (98.6)

   atp8

8

16

757

10

10 (2)

98.7

61.5 (88.9)

97.5 (98.5)

80.1 (93.8)

   atp9

19

91

792

1

17 (0)

99.9

84.3 (100.0)

98.0 (99.9)

92.1 (99.9)

Cytochrome c biogenesis

   ccmB

9

216

1013

14

63 (6)

98.6

77.4 (97.3)

94.1 (98.4)

88.0 (98.0)

   ccmC

9

187

1212

24

26 (1)

98.1

87.8 (99.5)

96.5 (98.2)

92.9 (98.8)

   ccmFc

6

84

1631

23

30 (10)

98.6

73.7 (89.4)

97.0 (98.1)

86.1 (94.0)

   ccmFn

6

155

2249

39

38 (21)

98.3

80.3 (88.1)

96.9 (97.6)

89.3 (93.2)

Ribosomal proteins

   rpl2

4

2

1057

14

6 (4)

98.7

25.0 (33.3)

98.1 (98.3)

61.8 (66.0)

   rpl5

9

45

919

14

5 (3)

98.5

90.0

98.1 (98.3)

94.2 (96.1)

   rpl6

3

0

138

3

0 (0)

97.9

-

97.9 (97.9)

-

   rpl16

9

33

692

6

13 (2)

99.1

71.7 (94.3)

97.4 (98.9)

85.4 (96.7)

   rps1

3

2

295

4

5 (5)

98.7

28.6 (28.6)

97.1 (97.1)

63.6 (63.6)

   rps2

7

25

1489

15

7 (5)

99.0

78.1 (83.3)

98.6 (98.7)

88.6 (91.2)

   rps3

7

54

2183

19

33 (11)

99.1

62.1 (83.1)

97.7 (98.7)

80.6 (91.1)

   rps4

6

83

1116

22

18 (6)

98.1

82.2 (93.3)

96.8 (97.7)

90.1 (95.7)

   rps7

8

6

664

19

2 (1)

97.2

75.0 (85.7)

97.0 (97.1)

86.1 (91.5)

   rps10

5

8

266

9

0 (0)

96.7

100.0 (100.0)

96.8 (96.8)

98.4 (98.4)

   rps11

3

0

222

1

0 (0)

99.6

-

99.6 (99.6)

-

   rps12

17

87

1142

13

5 (1)

98.9

94.6 (98.9)

98.6 (98.9)

96.7 (98.9)

   rps13

10

34

554

8

5 (2)

98.6

87.2 (94.4)

97.8 (98.3)

92.9 (96.5)

   rps14

5

2

239

7

0 (0)

97.2

100.0 (100.0)

(97.2) (97.2)

98.6 (98.6)

   rps19

6

16

242

11

9 (3)

95.7

64.0 (84.2)

92.8 (94.9)

79.8 (89.9)

Other

   matR

8

73

4109

30

20 (7)

99.3

78.5 (91.3)

98.8 (99.1)

88.9 (95.3)

   mttB

8

100

1087

41

23 (12)

96.4

81.3 (89.3)

94.9 (95.7)

88.8 (92.8)

Overall

370

3,038

55,956

609

660 (171)

98.9

82.2 (94.7)

97.9 (98.7)

90.5 (96.8)

  1. Values after exclusion of silent editing sites are shown in parentheses. In some cases (marked with a '-'), sensitivity and balanced accuracy could not be calculated because there were no known edited sites (i.e., TP + FN = 0).