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Table 1 Statistically significant SNPs (P < 0.05) relevant to esophageal squamous cell carcinoma. In 2000 runs of 10-fold cross-validation, nine SNPs were found to be the esophageal squamous cell carcinoma relevant. They had frequencies greater than the critical value of 0.028 at the 5% level of significance (P < 0.05).

From: Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method

No SNPs Frequency Gene function
  Gene RS number   
1 GADD45B E1122 0.186 DNA repair
2 NQO1 rs1800566 0.069 Phase II
3 adh1b_55   0.064 Alcohol-related
4 ERCC5 rs17655 0.064 DNA repair
5 COMT rs4818 0.052 Phase II
6 GADD45B rs14384 0.049 DNA repair
7 ercc5_55   0.048 DNA repair
8 CYP1A1 rs1048943 0.035 Phase I
9 GPX1_ rs1800668 0.030 Phase II
  1. RS – Reference SNP
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BMC Bioinformatics

ISSN: 1471-2105

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