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Table 2 Statistically significant SNP types relevant to esophageal squamous cell carcinoma. In 2000 runs of 10-fold cross-validation, 14 SNP types are found to be the esophageal squamous cell carcinoma relevant. They had frequencies greater than the critical value of 0.0095 at the 5% level of significance (P < 0.05). By applying these SNP types to the SNP data set, the first five SNP types have 95% confidence intervals (CIs) whose upper and lower limits not cross with OR = 1.

From: Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method

No OR 95% CI SNP site
    Gene RS number Genotype
1 1.66 1.16 – 2.37 GADD45B E1122 Homozygous common
2 1.50 1.05 – 2.15 ercc5_55   Homozygous common
3 1.44 1.00 – 2.06 COMT rs4818 Homozygous common
4 0.55 0.38 – 0.79 GADD45B E1122 Heterozygous
5 0.45 0.23 – 0.87 NQO1 rs1800566 Homozygous variant
6 1.64 0.70 – 3.87 ERCC5 rs17655 Homozygous variant
7 1.57 0.76 – 3.26 GPX1 rs1800668 Homozygous variant
8 1.43 0.98 – 2.09 NQO1 rs1800566 Heterozygous
9 1.05 0.73 – 1.52 ERCC2 rs1052559 Heterozygous
10 1.00 0.51 – 1.97 GADD45B rs14384 Homozygous variant
11 0.99 0.51 – 1.91 CYP1A1 rs1048943 Homozygous variant
12 0.87 0.60 – 1.26 cyp1a2_5   Heterozygous
13 0.83 0.57 – 1.20 CYP1A2 rs2472304 Heterozygous
14 0.59 0.27 – 1.32 adh1b_55   Heterozygous
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