Figure 6
From: CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Mechanism of forming inter-peptides crosslink in-silico . Given two proteins bz and BZ with 2 and 1 cleavable sites respectively and a missed-cleavage level of 1, CLPM will check whether or not there are crosslinking sites in each peptide. For those peptides with crosslinking sites (c and d in bz and C in BZ), CLPM will generate intra-molecule crosslinks (shown in blue) and inter-molecule crosslinks (shown in pink)