Metabolite coupling in genome-scale metabolic networks

BMC Bioinformatics

Table 4 Preferentially uncoupled metabolite pairs in E. coli. The top preferentially uncoupled metabolite pairs in the E. coli metabolic network.

Metabolite	Metabolite	p-value
H+	Pyruvate	0.0001
ATP	Nicotinamide adenine dinucleotide phosphate	0.0001
ATP	Nicotinamide adenine dinucleotide phosphate – reduced	0.0001
ADP	Nicotinamide adenine dinucleotide	0.0001
ADP	Diphosphate	0.0001
ADP	Nicotinamide adenine dinucleotide – reduced	0.0001
ADP	Nicotinamide adenine dinucleotide phosphate – reduced	0.0001
ATP	Nicotinamide adenine dinucleotide – reduced	0.0002
Phosphate	Nicotinamide adenine dinucleotide – reduced	0.0002
H2O	2-Oxoglutarate	0.0003
Phosphate	Nicotinamide adenine dinucleotide	0.0003
H+	Phosphoenolpyruvate	0.0004
ADP	Nicotinamide adenine dinucleotide phosphate	0.0004
ADP	Pyruvate	0.0005
H+	D-Glucose	0.0006
ATP	Pyruvate	0.0006
H+	2-Oxoglutarate	0.0007
ATP	Nicotinamide adenine dinucleotide	0.0007
Phosphate	Pyruvate	0.0009

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