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# Table 3 Parameters derived from the SUP sequence representation

From: Selection of antisense oligonucleotides based on multiple predicted target mRNA structures

Parameter | Definition |
---|---|

f
_{
NS
}
| Number of bases in single-stranded region |

f
_{
NP
}
| Number of bases in double-stranded region |

f
_{
PS
}
| Percentage of bases in single-stranded region to the length of ODN |

f
_{
PP
}
| Percentage of bases in double-stranded region to the length of ODN |

f
_{
CS
}
| Maximum length of consecutive subsequence in single-stranded region |

f
_{
CP
}
| Maximum length of consecutive subsequence in base pairing |

f
_{5S}
| Maximum length of consecutive subsequence in single-stranded region counting from 5' terminal |

f
_{5P}
| Maximum length of consecutive subsequence in base pairing counting from 5' terminal |

f
_{3S}
| Maximum length of consecutive subsequence in single-stranded region counting from 3' terminal |

f
_{3P}
| Maximum length of consecutive subsequence in base pairing counting from 3' terminal |

f
_{
SC
}
| Structure consistency, {f}_{SC}=\frac{1}{n-1}{\displaystyle \sum _{i=1}^{n-1}E({S}_{i},{S}_{i-1})}, where E(x,y)=\{\begin{array}{ll}1,\hfill & x=y\ne \text{'}\text{U}\text{'}\hfill \\ 0,\hfill & x=\text{'}\text{U}\text{'},ory=\text{'}\text{U}\text{'}\hfill \\ \text{-1}\hfill & x\ne y,x\ne \text{'}\text{S}\text{'},y\ne \text{'}\text{P}\text{'}\hfill \end{array} |