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Table 1 Datasets and their correlations. The different datasets that were used in the study and the number of their constituent proteins and interactions. The total number of proteins is shown, as well as the number of proteins for which sequence information was obtainable and the number of orthologs found in the Mus musculus. The final four columns show the correlations between three factors, Evolutionary Distance (ED) as measured using Grishin's method, Abundance (A) and Number of interactions (I). P-values for these correlations were calculated, values in bold have a p-value greater than 0.03. The final column shows the result of a partial correlation, between evolutionary rate and number of interactions where abundance has been controlled for. The BIND datasets lacked expression information due to nomenclature issues.

From: Protein protein interactions, evolutionary rate, abundance and age

Dataset Number of Proteins Number of Interactions ED vs I ED vs A A vs I ED vs I. controled A
  Total Sequences Orthologs      
MIPS_GENETIC 1628 1618 903 5113 0.005 -0.4381 0.018 0.015
MIPS_PHYSICAL 4154 4124 2064 7458 -0.017 -0.410 -0.064 -0.048
BIND 4542 3999 2084 8649 -0.032 - - -
GRID 4907 4897 2381 17598 -0.118 -0.416 0.135 -0.069
MINT 4595 4590 2269 12582 -0.143 -0.407 0.174 -0.080
DIP_FULL 4773 4772 2354 15481 -0.121 -0.411 0.164 -0.059
DIP_CORE 2640 2640 1552 6600 -0.168 -0.397 0.176 -0.109
INTACT_UETZ 1328 1325 816 1438 -0.077 -0.391 -0.045 -0.103
INTACT_ITO 3245 3241 1675 4449 0.030 -0.4172 0.001 0.033
INTACT_GAVIN 1471 1467 1014 3957 -0.172 -0.431 0.172 -0.109
INTACT_SMALL 94 92 63 134 -0.208 -0.087 -0.122 -0.221
INTACT_HO 1577 1573 1036 3618 -0.227 -0.388 0.213 -0.160