Table 2 Consensus clusters and influential attributes identified for the MYOEPITHELIAL collection. The format is the same as Table 1. Complete information on the genes in the consensus clusters and full lists of attributes can be found in Additional Files 3 and 4.
Cluster no. | Consensus cluster | Gene symbol (LocusID) and attributes |
|---|---|---|
0 | 48 Genes | AKR1C2 (1646); ARHGAP1 (392); BLCAP (10904); CBR1 (873); COL1A1 (1277); COL5A2 (1290); CSRP2 (1466); CSTA (1475); DKK3 (27122); EIF2B2 (8892); FABP5 (2171); FBL (2091); FLJ20297 (55627); FZD6 (8323); GAPD (2597); GPI (2821); GSTO1 (9446); GSTP1 (2950); HNRPF (3185); ID2 (3398); ID3 (3399); IMPA2 (3613); KRT1 (3848); MT1B (4490); MT1F (4494); MT1G (4495); MT1K (4499); MT1X (4501); MT3 (4504); MTHFD2 (10797); NDRG1 (10397); PES1 (23481); PKM2 (5315); PPFIBP2 (8495); PRDX1 (5052); PRNP (5621); PTHLH (5744); PTRF (284119); S100A2 (6273); S100A7 (6278); SERPINB5 (5268); SERPINH1 (871); SHMT2 (6472); SPARC (6678); SPRR1B (6699); SURF4 (6836); TIMP3 (7078); UQCRFS1 (7386) |
| Â | Attributes | CC: cell; intracellular |
| Â | Â | BP: physiological process |
1 | 17 Genes | AREG (374); ATP1B3 (483); CAV1 (857); CD44 (960); CDH13 (1012); FAT2 (2196); GPC1 (2817); ITGA3 (3675); ITGA6 (3655); JAG1 (182); LGALS7 (3963); MAEA (10296); NLGN2 (57555); PCDHGA12 (26025); PLP2 (5355); SELE (6401); SLC1A5 (6510) |
|  | Attributes | CC: cell†; membrane; integral to membrane; plasma membrane; integral to plasma membrane |
| Â | Â | MF: binding |
| Â | Â | BP: cellular process; cell communication; physiological process; cell adhesion; cellular physiological process |
2 | 15 Genes | CCT2 (10576); CSNK1A1 (1452); CTSC (1075); CTSL (1514); DUSP6 (1848); EIF4A1 (1973); IGF1R (3480); MMP3 (4314); MYLK (4638); PLAT (5327); PRSS1 (5644); PRSS11 (5654); RAN (5901); SFN (2810); TIMP1 (7076) |
| Â | Attributes | MF: catalytic activity; binding; hydrolase activity |
|  |  | BP: protein metabolism†; physiological process†; metabolism†; cellular process |
3 | 9 Genes | EPAS1 (2034); KHSRP (8570); MYC (4609); POLR2A (5430); SNAI2 (6591); TBX3 (6926); TP73L (8626); TRIM28 (10155); TRIM29 (23650) |
|  | Attributes | CC: intracellular†; cell†; nucleus |
|  |  | MF: nucleic acid binding†; DNA binding†; binding†; transcription regulator activity; transcription factor activity |
|  |  | BP: transcription, DNA-dependent†; physiological process†; metabolism†; regulation of transcription, DNA-dependent; regulation of transcription; transcription from Pol II promoter |