Skip to main content

Table 3 Differentially expressed genes common to two independent transcript profiling studies of human breast tissue [26,32]. The table shows LUMINAL and MYOEPITHELIAL genes [26] that were identified also by a SAGE study [32]; the column labelled "Cluster" indicates the "Consensus cluster" to which the gene was assigned (taken from Table 1 or Table 2). †denotes genes present in genomic regions found to be altered in a CGH study of invasive ductal breast carcinomas [33].

From: Ensemble attribute profile clustering: discovering and characterizing groups of genes with similar patterns of biological features

Cluster Location Symbol (LocusID): description
0 6q21 CD24 (934): CD24 antigen, small cell lung carcinoma cluster 4 antigen
  †7q11.23 CLDN4 (1364): claudin 4
  12q13 ERBB3 (2065): v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
  †17q25.2 SLC9A3R1 (9368): solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
  †19pl3.3 GADD45B (4616): growth arrest and DNA-damage-inducible, β
1 14q32 TNFAIP2 (7127): tumor necrosis factor, α-induced protein 2
2 14q22-q24 ZFP36L1 (677): zinc finger protein 36, C3H type-like 1
Cluster Location Symbol (LocusID): description
0 2p25 ID2 (3398): inhibitor of DNA binding 2, dominant negative helix- loop- helix protein
  5q31.3-q32 SPARC (6678): secreted protein, acidic, cysteine-rich, osteonectin
  12p13 GAPD (2597): glyceraldehyde-3-phosphate dehydrogenase
  †17q21.3-q22.1 COL1A1 (1277): collagen, type I, α 1
1 1q22-q25 SELE (6401): selectin E, endothelial adhesion molecule 1
  † 4q13-q21 AREG (374): amphiregulin, schwannoma- derived growth factor
2 1p35.3 SFN (2810): stratifin
  † 10q26.3 PRSS11 (5654): protease, serine, 11 [IGF binding]
3 2p21-p16 EPAS1 (2034): endothelial PAS domain protein 1
  3q27-q29 TP73L (8626): tumor protein p73-like