Development of an unbiased statistical method for the analysis of unigenic evolution

BMC Bioinformatics

Table 3 Comparison of f_{expected missense} values for Pin1 codons.

Codon	f_{expected missense} this study	f_{expected missense} Deminoff et al.
Met (ATG)	1.00	1.00
Trp (TGG)	1.00	1.00
Cys (TGC)	0.83	0.76
Asp (GAC)	0.83	0.76
Asp (GAT)	0.70	0.76
Glu (GAA)	0.70	0.76
Glu (GAG)	0.83	0.76
Phe (TTC)	0.87	0.76
Phe (TTT)	0.77	0.76
His (CAC)	0.83	0.76
Lys (AAA)	0.77	0.76
Lys (AAG)	0.87	0.76
Asn (AAC)	0.87	0.76
Gln (CAG)	0.83	0.76
Tyr (TAC)	0.87	0.76
Ile (ATC)	0.90	0.72
Ala (GCC)	0.67	0.67
Ala (GCG)	0.67	0.67
Gly (GGA)	0.43	0.67
Gly (GGC)	0.67	0.67
Gly (GGG)	0.67	0.67
Gly (GGT)	0.43	0.67
Pro (CCA)	0.43	0.67
Pro (CCC)	0.67	0.67
Pro (CCG)	0.67	0.67
Pro (CCT)	0.43	0.67
Val (GTC)	0.78	0.67
Val (GTG)	0.78	0.67
Thr (ACC)	0.78	0.67
Thr (ACG)	0.78	0.67
Thr (ACT)	0.58	0.67
Ser (AGC)	0.83	0.76
Ser (AGT)	0.70	0.76
Ser (TCC)	0.78	0.67
Ser (TCT)	0.58	0.67
Ser (TCA)	0.58	0.67
Ser (TCG)	0.78	0.67
Leu (CTG)	0.61	0.43
Leu (CTC)	0.78	0.67
Arg (AGA)	0.69	0.72
Arg (AGG)	0.81	0.72
Arg (CGA)	0.39	0.62

ISSN: 1471-2105