Table 1 The performances of self-consistency, Jack-knife validation and n -fold (4-, 6-, 8-, 10-fold in this work) cross-validation for four well-studied PKs of PKA, CK2, ATM and S6K. The n- fold cross-validation has been performed for the large data sets (N ≥ 30).
From: PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theory
PPSP | PKA | CK2 | ATM | S6K | |||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Sn(%) | Sp(%) | Sn(%) | Sp(%) | Sn(%) | Sp(%) | Sn(%) | Sp(%) |
Self-consistency | 90.11 | 91.70 | 83.21 | 90.01 | 93.02 | 94.06 | 92.85 | 97.97 | |
Jack-knife | 90.11 | 90.46 | 83.21 | 88.44 | 86.05 | 91.89 | 92.86 | 91.05 | |
| Â | 4- | 90.11 | 90.43 | 81.02 | 87.90 | 86.37 | 90.14 | N/A | N/A |
n -fold cross-validation | 6- | 90.11 | 90.52 | 81.02 | 88.34 | 86.37 | 90.60 | N/A | N/A |
| Â | 8- | 90.11 | 90.45 | 81.75 | 88.48 | 86.05 | 90.65 | N/A | N/A |
| Â | 10- | 90.11 | 90.48 | 81.75 | 88.22 | 86.05 | 91.39 | N/A | N/A |
Data set (No.) | Positive | 173 | 142 | 43 | 14 | ||||
| Â | Negative | 8, 408 | 5, 332 | 2, 048 | 683 | ||||