Figure 6
From: SNPs3D: Candidate gene and SNP selection for association studies
Graphical Interface for the KnowledgeNet of candidate genes for hypertension. The four larger ovals circle the clusters of genes in each of the primary blood pressure regulation pathways. Oval symbols are used for genes involved in monogenic disease, rectangular symbols for the rest. Red indicates that one or more population SNPs are classified as harmful at the molecular level. Italic red text indicates that one or more population SNPs with population frequency information are predicted to be deleterious. The length and color of the edges represent the strength of the link between pairs of genes. Red edges link genes sharing the same abstracts. Short edges link genes sharing a large number of biological keywords. Subsets of nodes can be highlighted by a number of criteria, such as membership of the same KEGG pathway, or homology, or SNP frequency.