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Table 4 Sensitivities of the Dynalign/LIBSVM classifier, RNAz, and QRNA broken down by percent identity.

From: Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change

   % sensitivity % specificity
% identity range N % of real set Dynalign (P > 0.819) RNAz (P > 0.789) QRNA N % of negative set Dynalign (P <= 0.819) RNAz (P <= 0.789) QRNA
[0 10) 0 0 N/A N/A N/A 0 0 N/A N/A N/A
[10 20) 0 0 N/A N/A N/A 0 0 N/A N/A N/A
[20 30) 3 0.0033 100.0 0.0 66.6667 49 0.0271 97.9592 100.0 95.9184
[30 40) 1337 1.4767 71.4286 34.6298 48.6163 9037 4.9907 99.1922 97.0233 97.8975
[40 50) 22328 24.6612 63.6465 63.1539 46.5559 85008 46.9455 99.3612 98.8542 99.2789
[50 60) 42733 47.1984 73.0606 75.6488 56.2469 55602 30.7061 99.2320 99.5018 99.0306
[60 70) 17346 19.1586 88.4930 92.2461 86.0775 23952 13.2274 99.1566 99.3028 98.8143
[70 80) 4061 4.4854 94.5826 94.5087 94.1394 4672 2.5801 97.5813 98.4375 97.9238
[80 90) 2035 2.2477 95.5774 91.9410 93.9066 2062 1.1387 90.8341 98.1086 96.6052
[90 100) 654 0.7223 98.4709 72.6300 59.7859 654 0.3612 60.5505 96.7890 95.2599
[100 ] 42 0.0464 92.8571 61.9048 11.9048 42 0.0232 61.9048 90.4762 95.2381
totals 90539 100.0 75.3366 81.2854 62.0108 181078 100.0 98.9938 98.9927 98.9905
  1. A comparison of sensitivities of the three ncRNA classification/detection programs within each percent identity range. N is the number of sequences within each range. Probability cutoffs for RNAz and the Dynalign/LIBSVM classifier were selected such that overall specificities for the entire test set match the specificity of QRNA as closely as possible.