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Table 1 Coregulation Groups for Rosetta ROC Analysis. This table provides groups of genes that are believed to be coregulated based on the metabolic pathways of S. cerevisiae as summarized in the KEGG database.

From: LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates

Coregulation Groups

Group

KEGG Pathway

Genes

1

glucose fermentation

ADH5 ALD5 ADH4 ADH2 ADH1 ALD4

2

phenylalanine degradation

ADH5 ARO10 ADH4 ARO9 ADH2 ADH1

3

sulfate assimilation pathway II

MET10 MET3 ECM17 MET14 MET17 MET16

4

gluconeogenesis

TDH2 PCK1 YMR323W ERR1 ERR2

5

serine-isocitrate lyase pathway

CIT2 ACO1 YMR323W ERR1 ERR2

6

TCA cycle, aerobic respiration

CIT2 KGD2 ACO1 IDH1 IDH2

7

tryptophan degradation

ADH5 ARO10 ADH4 ADH2 ADH1

8

glycolysis

TDH2 YMR323W ERR1 ERR2

9

histidine biosynthesis

HIS7 HIS4 HIS5 HIS3

10

leucine biosynthesis

LEU2 LEU1 BAT1 LEU4

11

tryptophan degradation via kynurenine

BNA4 BNA1 BNA2 BNA5