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Table 2 Selection of GEPs using the criteria for functional effectiveness.

From: Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock

 

Values for Criteria

Percentage of GEPs selected using each criteria

 

Absolute values

Ratio to basal values

Individual

Accumulated

C1

VATPa > 180.6

3

45.13e

 

C2

VTREa > 0.03

25

60.95e

 

C3

VNADPHa > 3.54

2

85.86e

27.83

C4

GLCb < 0.04

1.2

86.40f

 
 

G6Pb < 20.22

20

76.04f

 
 

F16Pb < 22.86

2.5

51.91f

 
 

PEPb < 0.01

1.2

65.44f

 
 

ATPb < 6.77

6

89.32f

2.40

C5

Costc < 12.06

12.06

50

0.59

C6

VGlycerola > 0.39

0.22

50

0.25

C7

Ψd < 28.10

0.391

50

0.16

C8

F16Pb > 8.64

0.95

61.93

0.06

  1. (a) Rate of synthesis (mMmin-1). (b) Concentration (mM). (c) Adimensional. (d) mM-1min. (e) Application of C1-C3 selects 27.83% of all GEPs. (f) Application of constraints on all concentrations simultaneously selects 24.23% of all GEPs.