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Table 6 Control coefficients of elementary mode fluxes by individual steps at the experimental steady state. The bottom part of the table refers to the following processes: GLT, transport of glucose across the cell membrane; Glyco, glycogen branch; Treha, trehalose branch; Succ, succinate branch; AK, equilibrium constraint on adenylate kinase due to the conservation of adenine nucleotides.

From: Quantitative elementary mode analysis of metabolic pathways: the example of yeast glycolysis

Enzymes, processes

EM1

EM2

EM3

EM4

EM5

EM6

EM7

EM8

GLK

0

0

N/A

N/A

0.090

N/A

0.090

0.208

PGI

0

0

N/A

N/A

0.0013

N/A

0.0010

0.0030

PFK

0

0

N/A

N/A

0.0010

N/A

0.0009

0.0023

ALD

0

0

N/A

N/A

0.0002

N/A

0.0005

0.0004

G3PDH

0

0

N/A

N/A

0.563

N/A

0.562

-0.249

GAPDH

0

0

N/A

N/A

-0.246

N/A

-0.246

0.111

PGK

0

0

N/A

N/A

-0.0068

N/A

-0.0057

0.0026

PGM

0

0

N/A

N/A

-0.0056

N/A

-0.0049

0.0023

ENO

0

0

N/A

N/A

-0.015

N/A

-0.015

0.0067

PYK

0

0

N/A

N/A

-0.0076

N/A

-0.0072

0.0033

PDC

0

0

N/A

N/A

-0.0045

N/A

-0.0042

0.0019

ADH

0

0

N/A

N/A

-0.108

N/A

-0.109

0.049

GLT

0

0

N/A

N/A

0.573

N/A

0.574

1.316

Glyco

0

1

N/A

N/A

-0.056

N/A

-0.056

-0.115

Treha

1

0

N/A

N/A

-0.043

N/A

-0.043

-0.090

Succ

0

0

N/A

N/A

0.346

N/A

0.346

-0.153

AK

0

0

N/A

N/A

-0.093

N/A

-0.093

-0.095

Summation

1

1

N/A

N/A

0.989

N/A

0.990

1.004